Dr Mills wearing scrubs, standing with arms crossed

About Dr. Mills

Hi, I’m Dr. Jesse Mills. I’m glad you’re here.

For over two decades, I’ve devoted my medical practice to helping men live and stay well.

I believe that good health is about making smart choices. That starts with being informed. My medical advice is rooted in simple and straightforward science, and always delivered judgement free.

Bio

Dr. Jesse Mills is a board-certified urologist and a fellowship-trained male reproductive surgeon.

After completing his medical and surgical training, Dr. Mills founded the first comprehensive men’s clinic in Colorado, The Center for Men’s Health at The Urology Center of Colorado. In 2016, he founded the Men’s Clinic at UCLA, where he continues to serve as director. Dr. Mills also serves as the fellowship director of the UCLA male reproductive medicine and surgery program, where he helps train the next generation of surgeons, and as director of UCLA Urology Santa Monica.

Dr. Mills sees thousands of patients each year for a range of conditions such as low testosterone, sexual and ejaculatory dysfunction, male fertility and Peyronie’s disease. He has performed thousands of penile implants, vasectomy reversals, varicocelectomy and complex Peyronie's disease surgeries and Xiaflex injections. Dr. Mills has a special interest in restoring fertility and sexual function in men with spinal cord injuries. At UCLA, he also leads fertility preservation in the gender health, adult and adolescent oncology programs. He serves as a medical consultant for several Los Angeles professional sports teams, including the Chargers, Dodgers and Lakers.

Dr. Mills has decades of experience writing the literature in men’s health and has authored multiple peer-reviewed scientific papers and book chapters. He is the best-selling author of A Field Guide to Men’s Health. Dr. Mills is also a frequent presenter at national and international conferences. He is recognized as an international thought leader in men’s health and sexual and reproductive medicine.

Dr. Mills Tidbits

I love playing in the dirt: landscaping and planting bushes and trees. I'm currently cultivating a 13-tree citrus grove.



I have a cup of coffee every day at 3 o'clock. I drink from a personalized coffee mug my former fellows got me, which says, “It’s 3 o’clock somewhere.”


I have 2 standard poodles, Bert and Ernie, who could be service dogs if they weren’t such enthusiastic athletes and shameless seekers of affection.



I split my fitness goals between running 5 hour marathons and benching 300 pounds but never both in the same calendar year.



My favorite restaurant is staying home and cooking with my wife and, if they’re in town, my sons and their families.

Education

Medical Board Certification
Urology, American Board of Urology

Fellowship
Male Reproductive Medicine and Surgery, Baylor College of Medicine

Residency
Urology, University of Colorado Health Science Center

Internship
General Surgery, University of Colorado Health Science Center

Degree
MD, University of Iowa Hospitals and Clinics

Clinical Expertise

Male Fertility

  • World-renowned expert in microsurgery and management of all aspects of male fertility.
  • International lecturer on advanced techniques in microsurgical reconstruction of the male reproductive tract.
  • Prolific author in the field of medical and surgical management of male fertility.
  • Pioneered minimally invasive techniques for surgical sperm extraction.

Peryonie's Disease

  • Principal investigator for Collagenase Clostridium Histolyticum (Xiaflex) that led to FDA approval of the drug in 2013.
  • Performed more Xiaflex injections than any clinician in the world.
  • Busy surgical practice in management of complex Peyronie’s disease.

Penile Implant Surgery

  • Recognized as one of the first centers of excellence for penile implant surgery by Boston Scientific, the leading surgical brand for penile implants.
  • Continues to maintain center of excellence status annually by remaining one of the highest volume implanters in the nation, training future leaders and surgeons and consulting frequently with the engineering division at Boston Scientific to bring new innovations to the field.

Hypogonadism

  • Developer of many key protocols in the management of men with hypogonadism.
  • Member of advisory boards and best practices panels to rationally and safely treat men with hypogonadism.
  • Co-author of papers serving as the framework for managing fertility recovery in men treated with testosterone and anabolic steroids.

Professional Memberships

  • American Urological Association
  • American Society for Reproductive Medicine
  • Sexual Medicine Society of North America
  • International Society for Sexual Medicine
  • Founding Member, American Society for Men's Health
  • Society of Urologic Prosthetic Surgeons

Recognitions

  • Super Doctors® Southern California 2024-2026
  • Top Doctors, Los Angeles Magazine 2019-2021, 2024-2026
  • Los Angeles Dodgers Men’s Health Champion 2025
  • UCLA Health LGBTQ+ Champion

2025 Top Doctors Logo

Publications

PubMed Publications

Mills JN, Broderick GA, Tursi JP, Ayad M, Rezakhani T, Andrews J, Patel S, Trost L. Peyronie’s disease patients with pain: a post hoc analysis of the IMPRESS I/II studies. Transl Androl Urol 2026;15(7):245. doi: 10.21037/tau-2026-0280.

Khera M, Torres LO, Grober ED, Morgentaler A, Miner M, Jones TH, Mills JN, Salonia A. Male hypogonadism: recommendations from the Fifth International Consultation on Sexual Medicine (ICSM 2024). Sex Med Rev, October 2025.

Bettencourt A, Wu J, Borrell JA, Furtado TP, Mills JN, Jayadevan R, Eleswarapu SV. Ejaculatory function after robotic waterjet ablation for the treatment of benign prostatic hyperplasia: a systematic review. Int J Impot Res, May 2025.

Borrell JA, Bettencourt A, Furtado TP, Rizzo A, Andino JJ, Eleswarapu SV, Mills JN. Exploring the Clinical Landscape of Priapism Related to Intracavernosal Injection Therapy: Patient Characteristics, Management Patterns, and Erectile Dysfunction Outcomes. Urology, April 2025.

Borrell JA, Bettencourt A, Furtado TP, Gu C, Ye N, Andino JJ, Eleswarapu SV, Mills JN. Risk factors, diagnosis, and long-term erectile dysfunction outcomes in priapism: a retrospective analysis of 186 cases from a single institution. Int J Impot Res, April 2025.

El-Achkar A, Hammad M, Barham D, Service CA, Patel D, Hsieh TC, Mills J, Kianian R, Eleswarapu S, Ziegelmann M, Smith R, Bryk D, Bernie HL, Egert M, Raheem O, Fendereski K, Gross K, Pastuszak A, Hotaling J, Yafi F. Stripping versus ligation of vas deferens in microscopic denervation of spermatic cord in men with chronic orchialgia: A multicenter study. Andrology, February 2025.

Borrell JA, Gu C, Ye N, Mills JN, Andino JJ. Comparing vasectomy techniques, recovery and complications: tips and tricks. Int J Impot Res, January 2025.

Furtado TP, Osadchiy V, Andino JJ, Eleswarapu SV, Mills JN. Collagenase Clostridium histolyticum for Peyronie’s disease: a contemporary atlas of complications and their management. Sexual Medicine Reviews, March 2024.

Osadchiy V, Munoz-Lopez C, Jiang T, Naelitz B, Parekh N, Vij S, Mills JN, Lundy S, Eleswarapu SV. Combination clomiphene citrate and anastrozole duotherapy improves semen parameters in a multi-institutional, retrospective cohort of infertile men. Transl Androl Urol, February 2024.

Osadchiy V, Belarmino A, Kianian R, Sigalos JT, Furtado TP, Ancira JS, Kanie T, Mangum SF, Tipton CD, Hsieh TM, Mills JN, Eleswarapu SV. Urine microbes and predictive metagenomic profiles associate with abnormalities in sperm parameters: Implications for male subfertility. F&S Science, February 2024.

Sollender GE, Belarmino A, Furtado TP, Osadchiy V, Mills JN, Pellegrini M, Eleswarapu SV. The Interplay of Varicoceles, Sperm Epigenetics, and Male Infertility: A Focused, Contemporary Review. Andrologia, February 2024.

Medical Journal Peer Reviewer

  • Fertility and Sterility
  • International Journal of Impotence Research
  • Journal of Sexual Medicine
  • Journal of Urology
  • Sexual Medicine Reviews (former Associate Editor)
  • The British Medical Journal 
  • Translational Andrology and Urology